Transcriptional Profiling Identifies the Signaling Axes of IGF and Transforming Growth Factor-β as Involved in the Pathogenesis of Osteosarcoma

BACKGROUND: Osteosarcoma is the most common primary bone tumor in adolescents associated with skeletal development. The molecular pathogenesis of osteosarcoma has not been completely determined, although many molecular alterations have been found in human osteosarcomas and cell lines. QUESTIONS/PURP...

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Bibliografiske detaljer
Udgivet i:Clin Orthop Relat Res
Main Authors: Yang, Rui, Piperdi, Sajida, Zhang, Yue, Zhu, Wei, Neophytou, Neophytos, Hoang, Bang H., Mason, Gary, Geller, David, Dorfman, Howard, Meyers, Paul A., Healey, John H., Phinney, Donald G., Gorlick, Richard
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2015
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686509/
https://ncbi.nlm.nih.gov/pubmed/26463566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11999-015-4578-1
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