Transcriptional Profiling Identifies the Signaling Axes of IGF and Transforming Growth Factor-β as Involved in the Pathogenesis of Osteosarcoma

BACKGROUND: Osteosarcoma is the most common primary bone tumor in adolescents associated with skeletal development. The molecular pathogenesis of osteosarcoma has not been completely determined, although many molecular alterations have been found in human osteosarcomas and cell lines. QUESTIONS/PURP...

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Gepubliceerd in:Clin Orthop Relat Res
Hoofdauteurs: Yang, Rui, Piperdi, Sajida, Zhang, Yue, Zhu, Wei, Neophytou, Neophytos, Hoang, Bang H., Mason, Gary, Geller, David, Dorfman, Howard, Meyers, Paul A., Healey, John H., Phinney, Donald G., Gorlick, Richard
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer US 2015
Onderwerpen:
Basic Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686509/
https://ncbi.nlm.nih.gov/pubmed/26463566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11999-015-4578-1
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