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Are sirtuins viable targets for improving healthspan and lifespan?

Although the increased lifespan of our populations illustrates the success of modern medicine, the risk of developing many diseases increases exponentially with old age. Caloric restriction is known to retard ageing and delay functional decline as well as the onset of disease in most organisms. Stud...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nat Rev Drug Discov
Main Authors: Baur, Joseph A., Ungvari, Zoltan, Minor, Robin K., Couteur, David G. Le, de Cabo, Rafael
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684642/
https://ncbi.nlm.nih.gov/pubmed/22653216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd3738
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