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Are sirtuins viable targets for improving healthspan and lifespan?

Although the increased lifespan of our populations illustrates the success of modern medicine, the risk of developing many diseases increases exponentially with old age. Caloric restriction is known to retard ageing and delay functional decline as well as the onset of disease in most organisms. Stud...

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Podrobná bibliografie
Vydáno v:Nat Rev Drug Discov
Hlavní autoři: Baur, Joseph A., Ungvari, Zoltan, Minor, Robin K., Couteur, David G. Le, de Cabo, Rafael
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684642/
https://ncbi.nlm.nih.gov/pubmed/22653216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd3738
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