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Are sirtuins viable targets for improving healthspan and lifespan?

Although the increased lifespan of our populations illustrates the success of modern medicine, the risk of developing many diseases increases exponentially with old age. Caloric restriction is known to retard ageing and delay functional decline as well as the onset of disease in most organisms. Stud...

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Dades bibliogràfiques
Publicat a:Nat Rev Drug Discov
Autors principals: Baur, Joseph A., Ungvari, Zoltan, Minor, Robin K., Couteur, David G. Le, de Cabo, Rafael
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684642/
https://ncbi.nlm.nih.gov/pubmed/22653216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd3738
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