AP39, a mitochondrially- targeted hydrogen sulfide donor, exerts protective effects in renal epithelial cells subjected to oxidative stress in vitro and in acute renal injury in vivo

This study evaluated the effects of AP39 [(10-oxo-10-(4-(3-thioxo-3H-1,2-dithiol-5yl) phenoxy)decyl) triphenyl phosphonium bromide], a mitochondrially targeted donor of hydrogen sulfide (H(2)S) in an in vitro model of hypoxia/oxidative stress injury in NRK-49F rat kidney epithelial cells (NRK cells)...

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Publicado en:Shock
Main Authors: Ahmad, Akbar, Olah, Gabor, Szczesny, Bartosz, Wood, Mark E., Whiteman, Matthew, Szabo, Csaba
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684477/
https://ncbi.nlm.nih.gov/pubmed/26513708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000478
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