Full-Length Trimeric Influenza Virus Hemagglutinin II Membrane Fusion Protein and Shorter Constructs Lacking the Fusion Peptide or Transmembrane Domain: Hyperthermostability of the Full-Length Protein and the Soluble Ectodomain and Fusion Peptide Make Significant Contributions to Fusion of Membrane Vesicles()

Influenza virus is a Class I enveloped virus which is initially endocytosed into a host respiratory epithelial cell. Subsequent reduction of the pH to the 5–6 range triggers a structural change of the viral hemagglutinin II (HA2) protein, fusion of the viral and endosomal membranes, and release of t...

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Bibliographic Details
Published in:Protein Expr Purif
Main Authors: Ratnayake, Punsisi U., Ekanayaka, E. A. Prabodha, Komanduru, Sweta S., Weliky, David P.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684446/
https://ncbi.nlm.nih.gov/pubmed/26297995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2015.08.021
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