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Potentiation of Neuronal Nicotinic Receptors by 17β-Estradiol: Roles of the Carboxy-Terminal and the Amino-Terminal Extracellular Domains

The endogenous steroid 17β-estradiol (βEST) potentiates activation of neuronal nicotinic receptors containing α4 subunits. Previous work has shown that the final 4 residues of the α4 subunit are required for potentiation. However, receptors containing the α2 subunit are not potentiated although it h...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jin, Xiaochun, Steinbach, Joe Henry
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684330/
https://ncbi.nlm.nih.gov/pubmed/26684647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144631
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