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A Portable Site: A Binding Element for 17β-Estradiol Can Be Placed on Any Subunit of a Nicotinic α4β2 Receptor

Endogenous steroids can modulate the activity of transmitter-gated channels by directly interacting with the receptor. 17β-Estradiol potentiates activation of neuronal nicotinic α4β2 receptors by interacting with a 4 aa sequence at the extreme C terminus of the α4 subunit, but it is not known whethe...

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Библиографические подробности
Главные авторы: Jin, Xiaochun, Steinbach, Joe Henry
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081638/
https://ncbi.nlm.nih.gov/pubmed/21451042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4802-10.2011
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