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Efficacy and Safety of Methylnaltrexone for Opioid-Induced Constipation in Patients With Chronic Noncancer Pain: A Placebo Crossover Analysis

In patients with chronic noncancer pain, subcutaneous methylnaltrexone for opioid-induced constipation (OIC) was examined in a randomized controlled trial (RCT) followed by an open-label extension (OLE). This study examined the reproducibility of RCT findings by analyzing data from placebo-treated p...

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Detalhes bibliográficos
Publicado no:Reg Anesth Pain Med
Main Authors: Viscusi, Eugene R., Barrett, Andrew C., Paterson, Craig, Forbes, William P.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684250/
https://ncbi.nlm.nih.gov/pubmed/26650429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/AAP.0000000000000341
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