Safety of oral methylnaltrexone for opioid-induced constipation in patients with chronic noncancer pain

PURPOSE: Oral methylnaltrexone was shown to be effective in treating opioid-induced constipation (OIC) in patients with chronic noncancer pain in a Phase III randomized controlled trial. This report provides a detailed safety analysis from that study. METHODS: Adults (n=803) with chronic noncancer p...

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Veröffentlicht in:J Pain Res
Hauptverfasser: Rauck, Richard L, Slatkin, Neal E, Stambler, Nancy, Israel, Robert J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2018
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307492/
https://ncbi.nlm.nih.gov/pubmed/30613162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S170086
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