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Safety of oral methylnaltrexone for opioid-induced constipation in patients with chronic noncancer pain

PURPOSE: Oral methylnaltrexone was shown to be effective in treating opioid-induced constipation (OIC) in patients with chronic noncancer pain in a Phase III randomized controlled trial. This report provides a detailed safety analysis from that study. METHODS: Adults (n=803) with chronic noncancer p...

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Опубликовано в: :J Pain Res
Главные авторы: Rauck, Richard L, Slatkin, Neal E, Stambler, Nancy, Israel, Robert J
Формат: Artigo
Язык:Inglês
Опубликовано: Dove Medical Press 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307492/
https://ncbi.nlm.nih.gov/pubmed/30613162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S170086
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