Pro-inflammatory pattern of IgG1 Fc glycosylation in multiple sclerosis cerebrospinal fluid

BACKGROUND: Immunoglobulin G (IgG) effector functions are regulated by the composition of glycans attached to a conserved N-glycosylation site in the Fc part. Intrathecal production of IgG, especially IgG1, is a hallmark of multiple sclerosis (MS), but nothing is known about IgG Fc glycosylation in...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Neuroinflammation
मुख्य लेखकों: Wuhrer, Manfred, Selman, Maurice H. J., McDonnell, Liam A., Kümpfel, Tania, Derfuss, Tobias, Khademi, Mohsen, Olsson, Tomas, Hohlfeld, Reinhard, Meinl, Edgar, Krumbholz, Markus
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2015
विषय:
Research
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683913/
https://ncbi.nlm.nih.gov/pubmed/26683050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0450-1
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