Bridging, switching or drug holidays – how to treat a patient who stops natalizumab?

Por Havla, Joachim, Kleiter, Ingo, Kümpfel, Tania
Publicado em 2013

Delayed diagnosis of extraovarian teratoma in relapsing anti-NMDA receptor encephalitis

Por Kümpfel, Tania, Gerdes, Lisa Ann, Heck, Clarissa, Prüss, Harald
Publicado no Neurol Neuroimmunol Neuroinflamm (2016)

Metabotropic glutamate receptor type 1 autoimmunity: Clinical features and treatment outcomes

Por Lopez-Chiriboga, A. Sebastian, Komorowski, Lars, Kümpfel, Tania, Probst, Christian, Hinson, Shannon R., Pittock, Sean J., McKeon, Andrew
Publicado no Neurology (2016)

Update on the diagnosis and treatment of neuromyelitis optica: Recommendations of the Neuromyelitis Optica Study Group (NEMOS)

Por Trebst, Corinna, Jarius, Sven, Berthele, Achim, Paul, Friedemann, Schippling, Sven, Wildemann, Brigitte, Borisow, Nadja, Kleiter, Ingo, Aktas, Orhan, Kümpfel, Tania
Publicado em 2013

Multiple sclerosis–like lesions and type I interferon signature in a patient with RVCL

Por Schuh, Elisabeth, Ertl-Wagner, Birgit, Lohse, Peter, Wolf, Waltraud, Mann, Johannes F., Lee-Kirsch, Min Ae, Hohlfeld, Reinhard, Kümpfel, Tania
Publicado no Neurol Neuroimmunol Neuroinflamm (2014)

Expanding spectrum of neurologic manifestations in patients with NLRP3 low-penetrance mutations

Por Schuh, Elisabeth, Lohse, Peter, Ertl-Wagner, Birgit, Witt, Matthias, Krumbholz, Markus, Frankenberger, Marion, Gerdes, Lisa-Ann, Hohlfeld, Reinhard, Kümpfel, Tania
Publicado no Neurol Neuroimmunol Neuroinflamm (2015)

Anti-CD20 B-cell depletion enhances monocyte reactivity in neuroimmunological disorders

Por Lehmann-Horn, Klaus, Schleich, Eva, Hertzenberg, Deetje, Hapfelmeier, Alexander, Kümpfel, Tania, von Bubnoff, Nikolas, Hohlfeld, Reinhard, Berthele, Achim, Hemmer, Bernhard, Weber, Martin S
Publicado em 2011

Very late-onset neuromyelitis optica spectrum disorder beyond the age of 75

Por Krumbholz, Markus, Hofstadt-van Oy, Ulrich, Angstwurm, Klemens, Kleiter, Ingo, Jarius, Sven, Paul, Friedemann, Aktas, Orhan, Buchholz, Grete, Kern, Peter, Straube, Andreas, Kümpfel, Tania
Publicado no J Neurol (2015)

Pro-inflammatory pattern of IgG1 Fc glycosylation in multiple sclerosis cerebrospinal fluid

Por Wuhrer, Manfred, Selman, Maurice H. J., McDonnell, Liam A., Kümpfel, Tania, Derfuss, Tobias, Khademi, Mohsen, Olsson, Tomas, Hohlfeld, Reinhard, Meinl, Edgar, Krumbholz, Markus
Publicado no J Neuroinflammation (2015)

Pathology of immune reconstitution inflammatory syndrome in multiple sclerosis with natalizumab-associated progressive multifocal leukoencephalopathy

Por Metz, Imke, Radue, Ernst-Wilhelm, Oterino, Agustin, Kümpfel, Tania, Wiendl, Heinz, Schippling, Sven, Kuhle, Jens, Sahraian, Mohammad Ali, Gray, Francoise, Jakl, Veronika, Häusler, Darius, Brück, Wolfgang
Publicado em 2011

CTLA4 as Immunological Checkpoint in the Development of Multiple Sclerosis

Por Gerdes, Lisa Ann, Held, Kathrin, Beltrán, Eduardo, Berking, Carola, Prinz, Jörg C., Junker, Andreas, Tietze, Julia K., Ertl‐Wagner, Birgit, Straube, Andreas, Kümpfel, Tania, Dornmair, Klaus, Hohlfeld, Reinhard
Publicado no Ann Neurol (2016)

Monthly intravenous methylprednisolone in relapsing-remitting multiple sclerosis - reduction of enhancing lesions, T2 lesion volume and plasma prolactin concentrations

Por Then Bergh, Florian, Kümpfel, Tania, Schumann, Erina, Held, Ulrike, Schwan, Michaela, Blazevic, Mirjana, Wismüller, Axel, Holsboer, Florian, Yassouridis, Alexander, Uhr, Manfred, Weber, Frank, Daumer, Martin, Trenkwalder, Claudia, Auer, Dorothee P
Publicado em 2006

Autoantibodies to MOG in a distinct subgroup of adult multiple sclerosis

Por Spadaro, Melania, Gerdes, Lisa Ann, Krumbholz, Markus, Ertl-Wagner, Birgit, Thaler, Franziska Sabrina, Schuh, Elisabeth, Metz, Imke, Blaschek, Astrid, Dick, Andrea, Brück, Wolfgang, Hohlfeld, Reinhard, Meinl, Edgar, Kümpfel, Tania
Publicado no Neurol Neuroimmunol Neuroinflamm (2016)

Histopathology and clinical course of MOG-antibody-associated encephalomyelitis

Por Spadaro, Melania, Gerdes, Lisa Ann, Mayer, Marie C, Ertl-Wagner, Birgit, Laurent, Sarah, Krumbholz, Markus, Breithaupt, Constanze, Högen, Tobias, Straube, Andreas, Giese, Armin, Hohlfeld, Reinhard, Lassmann, Hans, Meinl, Edgar, Kümpfel, Tania
Publicado no Ann Clin Transl Neurol (2015)

Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals

Por Derfuss, Tobias, Parikh, Khyati, Velhin, Sviataslau, Braun, Magdalena, Mathey, Emily, Krumbholz, Markus, Kümpfel, Tania, Moldenhauer, Anja, Rader, Christoph, Sonderegger, Peter, Pöllmann, Walter, Tiefenthaller, Christian, Bauer, Jan, Lassmann, Hans, Wekerle, Hartmut, Karagogeos, Domna, Hohlfeld, Reinhard, Linington, Christopher, Meinl, Edgar
Publicado em 2009

The immunoregulator soluble TACI is released by ADAM10 and reflects B-cell activation in autoimmunity

Por Hoffmann, Franziska S., Kuhn, Peer-Hendrik, Laurent, Sarah A., Hauck, Stefanie M., Berer, Kerstin, Wendlinger, Simone A., Krumbholz, Markus, Khademi, Mohsen, Olsson, Tomas, Dreyling, Martin, Pfister, Hans-Walter, Alexander, Tobias, Hiepe, Falk, Kümpfel, Tania, Crawford, Howard C., Wekerle, Hartmut, Hohlfeld, Reinhard, Lichtenthaler, Stefan F., Meinl, Edgar
Publicado no J Immunol (2014)

Cerebrospinal Fluid JC Virus Antibody Index for Diagnosis of Natalizumab-Associated Progressive Multifocal Leukoencephalopathy

Por Warnke, Clemens, von Geldern, Gloria, Markwerth, Philipp, Dehmel, Thomas, Hoepner, Robert, Gold, Ralf, Pawlita, Michael, Kümpfel, Tania, Mäurer, Mathias, Stangel, Martin, Wegner, Florian, Hohlfeld, Reinhard, Straeten, Vera, Limmroth, Volker, Weber, Thomas, Hermsen, Derik, Kleinschnitz, Christoph, Hartung, Hans-Peter, Wattjes, Mike P., Anders, Svenningson, Major, Eugene, Olsson, Tomas, Kieseier, Bernd C., Adams, Ortwin
Publicado em 2014

Treatment of optic neuritis with erythropoietin (TONE): a randomised, double-blind, placebo-controlled trial—study protocol

Por Diem, Ricarda, Molnar, Fanni, Beisse, Flemming, Gross, Nikolai, Drüschler, Katharina, Heinrich, Sven P, Joachimsen, Lutz, Rauer, Sebastian, Pielen, Amelie, Sühs, Kurt-Wolfram, Linker, Ralf Andreas, Huchzermeyer, Cord, Albrecht, Philipp, Hassenstein, Andrea, Aktas, Orhan, Guthoff, Tanja, Tonagel, Felix, Kernstock, Christoph, Hartmann, Kathrin, Kümpfel, Tania, Hein, Katharina, van Oterendorp, Christian, Grotejohann, Birgit, Ihorst, Gabriele, Maurer, Julia, Müller, Matthias, Volkmann, Martin, Wildemann, Brigitte, Platten, Michael, Wick, Wolfgang, Heesen, Christoph, Schiefer, Ulrich, Wolf, Sebastian, Lagrèze, Wolf A
Publicado no BMJ Open (2016)

Analysis of Plasminogen Genetic Variants in Multiple Sclerosis Patients

Por Sadovnick, A. Dessa, Traboulsee, Anthony L., Bernales, Cecily Q., Ross, Jay P., Forwell, Amanda L., Yee, Irene M., Guillot-Noel, Lena, Fontaine, Bertrand, Cournu-Rebeix, Isabelle, Alcina, Antonio, Fedetz, Maria, Izquierdo, Guillermo, Matesanz, Fuencisla, Hilven, Kelly, Dubois, Bénédicte, Goris, An, Astobiza, Ianire, Alloza, Iraide, Antigüedad, Alfredo, Vandenbroeck, Koen, Akkad, Denis A., Aktas, Orhan, Blaschke, Paul, Buttmann, Mathias, Chan, Andrew, Epplen, Joerg T., Gerdes, Lisa-Ann, Kroner, Antje, Kubisch, Christian, Kümpfel, Tania, Lohse, Peter, Rieckmann, Peter, Zettl, Uwe K., Zipp, Frauke, Bertram, Lars, Lill, Christina M, Fernandez, Oscar, Urbaneja, Patricia, Leyva, Laura, Alvarez-Cermeño, Jose Carlos, Arroyo, Rafael, Garagorri, Aroa M., García-Martínez, Angel, Villar, Luisa M., Urcelay, Elena, Malhotra, Sunny, Montalban, Xavier, Comabella, Manuel, Berger, Thomas, Fazekas, Franz, Reindl, Markus, Schmied, Mascha C., Zimprich, Alexander, Vilariño-Güell, Carles
Publicado no G3 (Bethesda) (2016)

MANBA, CXCR5, SOX8, RPS6KB1 and ZBTB46 are genetic risk loci for multiple sclerosis

Por Lill, Christina M., Schjeide, Brit-Maren M., Graetz, Christiane, Ban, Maria, Alcina, Antonio, Ortiz, Miguel A., Pérez, Jennifer, Damotte, Vincent, Booth, David, Lopez de Lapuente, Aitzkoa, Broer, Linda, Schilling, Marcel, Akkad, Denis A., Aktas, Orhan, Alloza, Iraide, Antigüedad, Alfredo, Arroyo, Rafa, Blaschke, Paul, Buttmann, Mathias, Chan, Andrew, Compston, Alastair, Cournu-Rebeix, Isabelle, Dörner, Thomas, Epplen, Joerg T., Fernández, Óscar, Gerdes, Lisa-Ann, Guillot-Noël, Léna, Hartung, Hans-Peter, Hoffjan, Sabine, Izquierdo, Guillermo, Kemppinen, Anu, Kroner, Antje, Kubisch, Christian, Kümpfel, Tania, Li, Shu-Chen, Lindenberger, Ulman, Lohse, Peter, Lubetzki, Catherine, Luessi, Felix, Malhotra, Sunny, Mescheriakova, Julia, Montalban, Xavier, Papeix, Caroline, Paredes, Lidia F., Rieckmann, Peter, Steinhagen-Thiessen, Elisabeth, Winkelmann, Alexander, Zettl, Uwe K., Hintzen, Rogier, Vandenbroeck, Koen, Stewart, Graeme, Fontaine, Bertrand, Comabella, Manuel, Urcelay, Elena, Matesanz, Fuencisla, Sawcer, Stephen, Bertram, Lars, Zipp, Frauke
Publicado em 2013