Cerebrospinal Fluid JC Virus Antibody Index for Diagnosis of Natalizumab-Associated Progressive Multifocal Leukoencephalopathy

OBJECTIVE: Progressive multifocal leukoencephalopathy (PML), caused by JC virus (JCV), can occur in patients receiving natalizumab for multiple sclerosis (MS). JCV detection by quantitative polymerase chain reaction (qPCR) in cerebrospinal fluid (CSF), or brain biopsy, is required for probable or de...

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Main Authors: Warnke, Clemens, von Geldern, Gloria, Markwerth, Philipp, Dehmel, Thomas, Hoepner, Robert, Gold, Ralf, Pawlita, Michael, Kümpfel, Tania, Mäurer, Mathias, Stangel, Martin, Wegner, Florian, Hohlfeld, Reinhard, Straeten, Vera, Limmroth, Volker, Weber, Thomas, Hermsen, Derik, Kleinschnitz, Christoph, Hartung, Hans-Peter, Wattjes, Mike P., Anders, Svenningson, Major, Eugene, Olsson, Tomas, Kieseier, Bernd C., Adams, Ortwin
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4194179/
https://ncbi.nlm.nih.gov/pubmed/24729444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24153
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