Association of Progressive Multifocal Leukoencephalopathy Lesion Volume With JC Virus Polymerase Chain Reaction Results in Cerebrospinal Fluid of Natalizumab-Treated Patients With Multiple Sclerosis

IMPORTANCE: The JC virus (JCV) was named after the first patient to be described with progressive multifocal leukoencephalopathy (PML), John Cunningham. Detection of JC virus DNA in cerebrospinal fluid (CSF) by polymerase chain reaction (PCR), and of specific lesions by brain magnetic resonance imag...

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Bibliographic Details
Published in:JAMA Neurol
Main Authors: Wijburg, Martijn T., Kleerekooper, Iris, Lissenberg-Witte, Birgit I., de Vos, Marlieke, Warnke, Clemens, Uitdehaag, Bernard M. J., Barkhof, Frederik, Killestein, Joep, Wattjes, Mike P.
Format: Artigo
Language:Inglês
Published: American Medical Association 2018
Subjects:
Original Investigation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885213/
https://ncbi.nlm.nih.gov/pubmed/29532061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2018.0094
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