Anti-CD20 B-cell depletion enhances monocyte reactivity in neuroimmunological disorders

BACKGROUND: Clinical trials evaluating anti-CD20-mediated B-cell depletion in multiple sclerosis (MS) and neuromyelitis optica (NMO) generated encouraging results. Our recent studies in the MS model experimental autoimmune encephalomyelitis (EAE) attributed clinical benefit to extinction of activate...

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Detalhes bibliográficos
Main Authors: Lehmann-Horn, Klaus, Schleich, Eva, Hertzenberg, Deetje, Hapfelmeier, Alexander, Kümpfel, Tania, von Bubnoff, Nikolas, Hohlfeld, Reinhard, Berthele, Achim, Hemmer, Bernhard, Weber, Martin S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214191/
https://ncbi.nlm.nih.gov/pubmed/22027448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-146
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