Anti-CD20 B-cell depletion enhances monocyte reactivity in neuroimmunological disorders

BACKGROUND: Clinical trials evaluating anti-CD20-mediated B-cell depletion in multiple sclerosis (MS) and neuromyelitis optica (NMO) generated encouraging results. Our recent studies in the MS model experimental autoimmune encephalomyelitis (EAE) attributed clinical benefit to extinction of activate...

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Bibliografische gegevens
Hoofdauteurs: Lehmann-Horn, Klaus, Schleich, Eva, Hertzenberg, Deetje, Hapfelmeier, Alexander, Kümpfel, Tania, von Bubnoff, Nikolas, Hohlfeld, Reinhard, Berthele, Achim, Hemmer, Bernhard, Weber, Martin S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2011
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214191/
https://ncbi.nlm.nih.gov/pubmed/22027448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-146
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