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Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity

Trafficking of cargo through the endosomal system depends on endosomal fusion events mediated by SNARE proteins, Rab-GTPases, and multisubunit tethering complexes. The CORVET and HOPS tethering complexes, respectively, regulate early and late endosomal tethering and have been characterized in detail...

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Vydáno v:J Biol Chem
Hlavní autoři: van der Kant, Rik, Jonker, Caspar T. H., Wijdeven, Ruud H., Bakker, Jeroen, Janssen, Lennert, Klumperman, Judith, Neefjes, Jacques
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683254/
https://ncbi.nlm.nih.gov/pubmed/26463206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.688440
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