SKIP‐HOPS recruits TBC1D15 for a Rab7‐to‐Arl8b identity switch to control late endosome transport

The endolysosomal system fulfils a myriad of cellular functions predicated on regulated membrane identity progressions, collectively termed maturation. Mature or “late” endosomes are designated by small membrane‐bound GTPases Rab7 and Arl8b, which can either operate independently or collaborate to f...

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Pubblicato in:EMBO J
Autori principali: Jongsma, Marlieke LM, Bakker, Jeroen, Cabukusta, Birol, Liv, Nalan, van Elsland, Daphne, Fermie, Job, Akkermans, Jimmy LL, Kuijl, Coenraad, van der Zanden, Sabina Y, Janssen, Lennert, Hoogzaad, Denise, van der Kant, Rik, Wijdeven, Ruud H, Klumperman, Judith, Berlin, Ilana, Neefjes, Jacques
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073467/
https://ncbi.nlm.nih.gov/pubmed/32080880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019102301
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