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Cholesterol and ORP1L-mediated ER contact sites control autophagosome transport and fusion with the endocytic pathway

Autophagy is the main homeostatic pathway guiding cytosolic materials for degradation by the lysosome. Maturation of autophagosomes requires their transport towards the perinuclear region of the cell, with key factors underlying both processes still poorly understood. Here we show that transport and...

詳細記述

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書誌詳細
出版年:Nat Commun
主要な著者: Wijdeven, Ruud H., Janssen, Hans, Nahidiazar, Leila, Janssen, Lennert, Jalink, Kees, Berlin, Ilana, Neefjes, Jacques
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906411/
https://ncbi.nlm.nih.gov/pubmed/27283760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11808
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