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Cholesterol-binding molecules MLN64 and ORP1L mark distinct late endosomes with transporters ABCA3 and NPC1

Cholesterol is an essential lipid in eukaryotic cells and is present in membranes of all intracellular compartments. A major source for cellular cholesterol is internalized lipoprotein particles that are transported toward acidic late endosomes (LE) and lysosomes. Here the lipoprotein particles are...

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Detalles Bibliográficos
Main Authors: van der Kant, Rik, Zondervan, Ilse, Janssen, Lennert, Neefjes, Jacques
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708365/
https://ncbi.nlm.nih.gov/pubmed/23709693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M037325
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