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Prostate Specific G-protein coupled Receptor collaborates with loss of PTEN to promote prostate cancer progression

Among frequent events in prostate cancer are loss of the tumor-suppressor phosphatase and tensin homologue (PTEN) and overexpression of Prostate-Specific G-protein-coupled Receptor (PSGR), but the potential tumorigenic synergy between these lesions is unknown. Here, we report a new mouse model (PSGR...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Rodriguez, Melissa, Siwko, Stefan, Zeng, Li, Li, Jinsong, Yi, Zhengfang, Liu, Mingyao
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683109/
https://ncbi.nlm.nih.gov/pubmed/26028029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.170
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