Mixed Lineage Leukemia 5 (MLL5) Protein Stability Is Cooperatively Regulated by O-GlcNac Transferase (OGT) and Ubiquitin Specific Protease 7 (USP7)

Mixed lineage leukemia 5 (MLL5) protein is a trithorax family histone 3 lysine 4 (H3K4) methyltransferase that regulates diverse biological processes, including cell cycle progression, hematopoiesis and cancer. The mechanisms by which MLL5 protein stability is regulated have remained unclear to date...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ding, Xiaodan, Jiang, Wei, Zhou, Peipei, Liu, Lulu, Wan, Xiaoling, Yuan, Xiujie, Wang, Xizi, Chen, Miao, Chen, Jun, Yang, Jing, Kong, Chao, Li, Bin, Peng, Chao, Wong, Catherine C. L., Hou, Fajian, Zhang, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683056/
https://ncbi.nlm.nih.gov/pubmed/26678539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145023
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