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Chemistry and biology of natural and designed enediynes.

Ever since the initial reports of the enediyne anticancer antibiotics in the late 1980s, researchers from a number of disciplines have been devoting increasing attention to their chemistry, biology, and potential medical applications. Synthetic chemists and molecular designers have been engaged in a...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Nicolaou, K C, Smith, A L, Yue, E W
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1993
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46830/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8327459/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.13.5881
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