Strain Prioritization and Genome Mining for Enediyne Natural Products

ABSTRACT The enediyne family of natural products has had a profound impact on modern chemistry, biology, and medicine, and yet only 11 enediynes have been structurally characterized to date. Here we report a genome survey of 3,400 actinomycetes, identifying 81 strains that harbor genes encoding the...

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Bibliographic Details

Main Authors:	Xiaohui Yan, Huiming Ge, Tingting Huang, Hindra, Dong Yang, Qihui Teng, Ivana Crnovčić, Xiuling Li, Jeffrey D. Rudolf, Jeremy R. Lohman, Yannick Gansemans, Xiangcheng Zhu, Yong Huang, Li-Xing Zhao, Yi Jiang, Filip Van Nieuwerburgh, Christoph Rader, Yanwen Duan, Ben Shen
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology 2016-12-01
Series:	mBio
Online Access:	https://journals.asm.org/doi/10.1128/mBio.02104-16
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