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Alzheimer's disease‐causing proline substitutions lead to presenilin 1 aggregation and malfunction
Do different neurodegenerative maladies emanate from the failure of a mutual protein folding mechanism? We have addressed this question by comparing mutational patterns that are linked to the manifestation of distinct neurodegenerative disorders and identified similar neurodegeneration‐linked prolin...
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| Publicado en: | EMBO J |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4682640/ https://ncbi.nlm.nih.gov/pubmed/26438723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201592042 |
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