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Modulation of caveolae by insulin/IGF‐1 signaling regulates aging of Caenorhabditis elegans
Reducing insulin/IGF‐1 signaling (IIS) extends lifespan, promotes protein homeostasis (proteostasis), and elevates stress resistance of worms, flies, and mammals. How these functions are orchestrated across the organism is only partially understood. Here, we report that in the nematode Caenorhabditi...
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| Publicado no: | EMBO Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6073070/ https://ncbi.nlm.nih.gov/pubmed/29945933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201745673 |
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