The insulin/IGF signaling cascade modulates SUMOylation to regulate aging and proteostasis in Caenorhabditis elegans

Although aging-regulating pathways were discovered a few decades ago, it is not entirely clear how their activities are orchestrated, to govern lifespan and proteostasis at the organismal level. Here, we utilized the nematode Caenorhabditis elegans to examine whether the alteration of aging, by redu...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Moll, Lorna, Roitenberg, Noa, Bejerano-Sagie, Michal, Boocholez, Hana, Carvalhal Marques, Filipa, Volovik, Yuli, Elami, Tayir, Siddiqui, Atif Ahmed, Grushko, Danielle, Biram, Adi, Lampert, Bar, Achache, Hana, Ravid, Tommer, Tzur, Yonatan B, Cohen, Ehud
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2018
Konular:
Cell Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277199/
https://ncbi.nlm.nih.gov/pubmed/30403374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.38635
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