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Protein Quality Control in Health and Disease

Maintaining functional protein homeostasis (proteostasis) is a constant challenge in the face of limited protein-folding capacity, environmental threats, and aging. Cells have developed several quality-control mechanisms that assist nascent polypeptides to fold properly, clear misfolded molecules, r...

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Publicat a:Cold Spring Harb Perspect Biol
Autors principals: Dubnikov, Tatyana, Ben-Gedalya, Tziona, Cohen, Ehud
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334259/
https://ncbi.nlm.nih.gov/pubmed/27864315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a023523
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