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A Cysteine Substitution Probes β3H267 Interactions with Propofol and Other Potent Anesthetics in α1β3γ2L Gamma-Aminobutyric Acid Type A Receptors
BACKGROUND: Anesthetic contact residues in γ-aminobutyric acid type A (GABA(A)) receptors have been identified using photolabels, including two propofol derivatives. O-propofol-diazirine labels H267 in β3 and α1β3 receptors, while m-azi-propofol labels other residues in intersubunit clefts of α1β3....
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| Publicado no: | Anesthesiology |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4681607/ https://ncbi.nlm.nih.gov/pubmed/26569173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000934 |
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