Comprehensive spectrum of BRCA1 and BRCA2 deleterious mutations in breast cancer in Asian countries

Approximately 5%–10% of breast cancers are due to genetic predisposition caused by germline mutations; the most commonly tested genes are BRCA1 and BRCA2 mutations. Some mutations are unique to one family and others are recurrent; the spectrum of BRCA1/BRCA2 mutations varies depending on the geograp...

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Foilsithe in:J Med Genet
Main Authors: Kwong, Ava, Shin, Vivian Y, Ho, John C W, Kang, Eunyoung, Nakamura, Seigo, Teo, Soo-Hwang, Lee, Ann S G, Sng, Jen-Hwei, Ginsburg, Ophira M, Kurian, Allison W, Weitzel, Jeffrey N, Siu, Man-Ting, Law, Fian B F, Chan, Tsun-Leung, Narod, Steven A, Ford, James M, Ma, Edmond S K, Kim, Sung-Won
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4681590/
https://ncbi.nlm.nih.gov/pubmed/26187060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2015-103132
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