Identification of BRCA1/2 Founder Mutations in Southern Chinese Breast Cancer Patients Using Gene Sequencing and High Resolution DNA Melting Analysis

BACKGROUND: Ethnic variations in breast cancer epidemiology and genetics have necessitated investigation of the spectra of BRCA1 and BRCA2 mutations in different populations. Knowledge of BRCA mutations in Chinese populations is still largely unknown. We conducted a multi-center study to characteriz...

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Detalhes bibliográficos
Main Authors: Kwong, Ava, Ng, Enders Kai On, Wong, Chris Lei Po, Law, Fian Bic Fai, Au, Tommy, Wong, Hong Nei, Kurian, Allison W., West, Dee W., Ford, James M., Ma, Edmond Siu Kwan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436879/
https://ncbi.nlm.nih.gov/pubmed/22970155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043994
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