Identification of BRCA1/2 Founder Mutations in Southern Chinese Breast Cancer Patients Using Gene Sequencing and High Resolution DNA Melting Analysis

BACKGROUND: Ethnic variations in breast cancer epidemiology and genetics have necessitated investigation of the spectra of BRCA1 and BRCA2 mutations in different populations. Knowledge of BRCA mutations in Chinese populations is still largely unknown. We conducted a multi-center study to characteriz...

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Bibliografiske detaljer
Main Authors: Kwong, Ava, Ng, Enders Kai On, Wong, Chris Lei Po, Law, Fian Bic Fai, Au, Tommy, Wong, Hong Nei, Kurian, Allison W., West, Dee W., Ford, James M., Ma, Edmond Siu Kwan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436879/
https://ncbi.nlm.nih.gov/pubmed/22970155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043994
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