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Mechanistic Studies on the Application of DNA Aptamers as Inhibitors of 2-Oxoglutarate-Dependent Oxygenases
The Escherichia coli (E. coli) AlkB protein and its functional human homologues belong to a subfamily of 2-oxoglutarate (2OG)-dependent oxygenases (2OG oxygenases for simplicity) that enable the repair of cytotoxic methylation damage in nucleic acids and which catalyse t-RNA oxidations. DNA alkylati...
Gorde:
| Argitaratua izan da: | J Med Chem |
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| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2012
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4681096/ https://ncbi.nlm.nih.gov/pubmed/22471443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm300243h |
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