Llwytho...

Post-licensing specification of eukaryotic replication origins by facilitated Mcm2-7 sliding along DNA

Eukaryotic genomes are replicated from many origin sites that are licensed by the loading of the replicative DNA helicase, Mcm2-7. How eukaryotic origin positions are specified remains elusive. Here we show that, contrary to the bacterial paradigm, eukaryotic replication origins are not irrevocably...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell
Prif Awduron: Gros, Julien, Kumar, Charanya, Lynch, Gerard, Yadav, Tejas, Whitehouse, Iestyn, Remus, Dirk
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4680849/
https://ncbi.nlm.nih.gov/pubmed/26656162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.10.022
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