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Post-licensing specification of eukaryotic replication origins by facilitated Mcm2-7 sliding along DNA
Eukaryotic genomes are replicated from many origin sites that are licensed by the loading of the replicative DNA helicase, Mcm2-7. How eukaryotic origin positions are specified remains elusive. Here we show that, contrary to the bacterial paradigm, eukaryotic replication origins are not irrevocably...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4680849/ https://ncbi.nlm.nih.gov/pubmed/26656162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.10.022 |
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