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Eukaryotic replication origins: Strength in flexibility
The eukaryotic replicative DNA helicase, Mcm2-7, is loaded in inactive form as a double hexameric complex around double-stranded DNA. To ensure that replication origins fire no more than once per S phase, activation of the Mcm2-7 helicase is temporally separated from Mcm2-7 loading in the cell cycle...
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| Publicado en: | Nucleus |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4991242/ https://ncbi.nlm.nih.gov/pubmed/27416360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2016.1187353 |
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