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Mechanism of Thermal Adaptation in the Lactate Dehydrogenases

The mechanism of thermal adaptation of enzyme function at the molecular level is poorly understood but is thought to lie within the structure of the protein or its dynamics. Our previous work on pig heart lactate dehydrogenase (phLDH) has determined very high resolution structures of the active site...

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Detalles Bibliográficos
Publicado en:J Phys Chem B
Main Authors: Peng, Huo-Lei, Egawa, Tsuyoshi, Chang, Eric, Deng, Hua, Callender, Robert
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679558/
https://ncbi.nlm.nih.gov/pubmed/26556099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.5b09909
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