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Mechanism of Thermal Adaptation in the Lactate Dehydrogenases

The mechanism of thermal adaptation of enzyme function at the molecular level is poorly understood but is thought to lie within the structure of the protein or its dynamics. Our previous work on pig heart lactate dehydrogenase (phLDH) has determined very high resolution structures of the active site...

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Vydáno v:J Phys Chem B
Hlavní autoři: Peng, Huo-Lei, Egawa, Tsuyoshi, Chang, Eric, Deng, Hua, Callender, Robert
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679558/
https://ncbi.nlm.nih.gov/pubmed/26556099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.5b09909
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