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Thermodynamic and Structural Adaptation Differences between the Mesophilic and Psychrophilic Lactate Dehydrogenases

The thermodynamics of substrate binding and enzymatic activity of a glycolytic enzyme, lactate dehydrogenase (LDH), from both porcine heart, phLDH (Sus scrofa; a mesophile), and mackerel icefish, cgLDH (Chamapsocephalus gunnari; a psychrophile), were investigated. Using a novel and quite sensitive f...

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Bibliografski detalji
Izdano u:Biochemistry
Glavni autori: Khrapunov, Sergei, Chang, Eric, Callender, Robert H.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574168/
https://ncbi.nlm.nih.gov/pubmed/28627164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00156
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