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Dietary obesity reversibly induces synaptic stripping by microglia and impairs hippocampal plasticity

Obesity increases risk of age-related cognitive decline and is accompanied by peripheral inflammation. Studies in rodent models of obesity have demonstrated that impaired hippocampal function correlates with microglial activation, but the possibility that neuron/microglia interactions might be pertu...

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Publicat a:Brain Behav Immun
Autors principals: Hao, Shuai, Dey, Aditi, Yu, Xiaolin, Stranahan, Alexis M.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679537/
https://ncbi.nlm.nih.gov/pubmed/26336035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2015.08.023
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