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Oligonucleotide gap-fill ligation for mutation detection and sequencing in situ

In clinical diagnostics a great need exists for targeted in situ multiplex nucleic acid analysis as the mutational status can offer guidance for effective treatment. One well-established method uses padlock probes for mutation detection and multiplex expression analysis directly in cells and tissues...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Mignardi, Marco, Mezger, Anja, Qian, Xiaoyan, La Fleur, Linnea, Botling, Johan, Larsson, Chatarina, Nilsson, Mats
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678841/
https://ncbi.nlm.nih.gov/pubmed/26240388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv772
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