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Assessing incomplete deprotection of microarray oligonucleotides in situ

En masse analysis of gene structure and function by array technologies will have a lasting and profound effect on biology and medicine. This impact can be compromised by low quality of probes within arrays, which we show can be caused by incomplete removal of chemical protecting groups. To solve thi...

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Autores principales: Dressman, Holly K., Barley-Maloney, Lise, Rowlette, Laura-Leigh, Agris, Paul F., Garcia-Blanco, Mariano A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636491/
https://ncbi.nlm.nih.gov/pubmed/17020916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl713
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