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In situ oligonucleotide synthesis on carbon materials: stable substrates for microarray fabrication

Glass has become the standard substrate for the preparation of DNA arrays. Typically, glass is modified using silane chemistries to provide an appropriate functional group for nucleic acid synthesis or oligonucleotide immobilization. We have found substantial issues with the stability of these surfa...

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Autori principali: Phillips, Margaret F., Lockett, Matthew R., Rodesch, Matthew J., Shortreed, Michael R., Cerrina, Franco, Smith, Lloyd M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2248760/
https://ncbi.nlm.nih.gov/pubmed/18084027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm1103
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