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In situ oligonucleotide synthesis on poly(dimethylsiloxane): a flexible substrate for microarray fabrication

In this paper, we demonstrate in situ synthesis of oligonucleotide probes on poly(dimethylsiloxane) (PDMS) microchannels through use of conventional phosphoramidite chemistry. PDMS polymer was moulded into a series of microchannels using standard soft lithography (micro-moulding), with dimensions &l...

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Détails bibliographiques
Auteurs principaux: Moorcroft, Matthew J., Meuleman, Wouter R. A., Latham, Steven G., Nicholls, Thomas J., Egeland, Ryan D., Southern, Edwin M.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2005
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1088307/
https://ncbi.nlm.nih.gov/pubmed/15870385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gni075
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