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Electrochemically directed synthesis of oligonucleotides for DNA microarray fabrication
We demonstrate a new method for making oligonucleotide microarrays by synthesis in situ. The method uses conventional DNA synthesis chemistry with an electrochemical deblocking step. Acid is delivered to specific regions on a glass slide, thus allowing nucleotide addition only at chosen sites. The a...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1183109/ https://ncbi.nlm.nih.gov/pubmed/16085751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gni117 |
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