In situ mutation detection and visualization of intratumor heterogeneity for cancer research and diagnostics

Current assays for somatic mutation analysis are based on extracts from tissue sections that often contain morphologically heterogeneous neoplastic regions with variable contents of genetically normal stromal and inflammatory cells, obscuring the results of the assays. We have developed an RNA-based...

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Detalhes bibliográficos
Main Authors: Grundberg, Ida, Kiflemariam, Sara, Mignardi, Marco, Imgenberg-Kreuz, Juliana, Edlund, Karolina, Micke, Patrick, Sundström, Magnus, Sjöblom, Tobias, Botling, Johan, Nilsson, Mats
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2013
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926836/
https://ncbi.nlm.nih.gov/pubmed/24280411
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