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Mutations in adenine-binding pockets enhance catalytic properties of NAD(P)H-dependent enzymes
NAD(P)H-dependent enzymes are ubiquitous in metabolism and cellular processes and are also of great interest for pharmaceutical and industrial applications. Here, we present a structure-guided enzyme engineering strategy for improving catalytic properties of NAD(P)H-dependent enzymes toward native o...
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| Publicat a: | Protein Eng Des Sel |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4678007/ https://ncbi.nlm.nih.gov/pubmed/26512129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzv057 |
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