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R-loops regulate promoter-proximal chromatin architecture and cellular differentiation
Numerous chromatin-remodeling factors are regulated by interactions with RNA, although the contexts and functions of RNA binding are poorly understood. Here we show that R-loops, RNA:DNA hybrids consisting of nascent transcripts hybridized to template DNA, modulate the binding of two key chromatin r...
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| Udgivet i: | Nat Struct Mol Biol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4677832/ https://ncbi.nlm.nih.gov/pubmed/26551076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3122 |
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