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Regulation of chromatin structure and cell fate by R-loops

Hybridization of RNA to its template DNA strand during transcription induces formation of R-loops—RNA:DNA hybrids with unpaired non-template DNA strands. Although unresolved R-loops can be detrimental, some R-loops contribute to regulation of chromatin structure. Consequently, R-loops help regulate...

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Bibliografische gegevens
Gepubliceerd in:Transcription
Hoofdauteur: Fazzio, Thomas G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984679/
https://ncbi.nlm.nih.gov/pubmed/27327157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541264.2016.1198298
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