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Strategies to improve delivery of anticancer drugs across the blood–brain barrier to treat glioblastoma

Glioblastoma (GBM) is a lethal and aggressive brain tumor that is resistant to conventional radiation and cytotoxic chemotherapies. Molecularly targeted agents hold great promise in treating these genetically heterogeneous tumors, yet have produced disappointing results. One reason for the clinical...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Oberoi, Rajneet K., Parrish, Karen E., Sio, Terence T., Mittapalli, Rajendar K., Elmquist, William F., Sarkaria, Jann N.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4677418/
https://ncbi.nlm.nih.gov/pubmed/26359209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov164
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