Aptamers Binding to c-Met Inhibiting Tumor Cell Migration

The human receptor tyrosine kinase c-Met plays an important role in the control of critical cellular processes. Since c-Met is frequently over expressed or deregulated in human malignancies, blocking its activation is of special interest for therapy. In normal conditions, the c-Met receptor is activ...

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Udgivet i:PLoS One
Main Authors: Piater, Birgit, Doerner, Achim, Guenther, Ralf, Kolmar, Harald, Hock, Bjoern
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4676636/
https://ncbi.nlm.nih.gov/pubmed/26658271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142412
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